Welcome to the lab of Richard Daneman
UC San DiegoDEPARTMENT of Neurosciences
DEPARTMENT of Pharmacology
2019
Weiner GA*, Shah SH*, Angelopoulos CM, Bartakova AB, Pulido RS, Murphy A, Nudleman E, Daneman R*, Goldberg JL*.
Nat Commun. 2019 Jun 6;10(1):2477. doi: 10.1038/s41467-019-10219-8.
Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties.
Stebbins MJ, Gastfriend BD, Canfield SG, Lee MS, Richards D, Faubion MG, Li WJ, Daneman R, Palecek SP, Shusta EV.
Sci Adv. 2019 Mar 13;5(3):eaau7375.
2018
2017
Blanchette M, Daneman R.
J Exp Med. 2017 Dec 4;214(12):3469-3470.
Brain barriers in health and disease.
Daneman R, Engelhardt B.
Neurobiol Dis. 2017 Nov;107:1-3.
Hindle SJ*, Munji RN*, Dolghih E, Gaskins G, Orng S, Ishimoto H, Soung A, DeSalvo M, Kitamoto T, Keiser MJ, Jacobson MP, Daneman R*, Bainton RJ*.
Cell Rep. 2017 Oct 31;21(5):1304-1316.
Goetzl EJ, Schwartz JB, Mustapic M, Lobach IV, Daneman R, Abner EL, Jicha GA.
FASEB J. 2017 Aug;31(8):3689-3694.
Meng Y, Wiseman JA, Nemtsova Y, Moore DF, Guevarra J, Reuhl K, Banks WA, Daneman R, Sleat DE, Lobel P.
Mol Ther. 2017 Jul 5;25(7):1531-1543.
2016
2015
Formation and maintenance of the BBB.
Blanchette M, Daneman R.
Mech Dev. 2015 Jul 24. pii: S0925-4773(15)30009-5
Sohet F, Lin C, Munji RN, Lee SY, Ruderisch N, Soung A, Arnold TD, Derugin N, Vexler ZS, Yen FT, Daneman R.
J Cell Biol. 2015 Mar 16;208(6):703-11
Daneman R, Prat A.
Cold Spring Harb Perspect Biol. 2015 Jan 5;7(1)
2014
Experimental cerebral malaria pathogenesis--hemodynamics at the blood brain barrier.
Nacer A, Movila A, Sohet F, Girgis NM, Gundra UM, Loke P, Daneman R, Frevert U.
PLoS Pathog. 2014 Dec 4;10(12):e1004528
Dissecting gene expression at the blood-brain barrier.
Huntley MA, Bien-Ly N, Daneman R, Watts RJ.
Front Neurosci. 2014 Nov 6;8:355
High endothelial venules through a transcriptomics lens.
Rosen SD, Daneman R.
Nat Immunol. 2014 Oct;15(10):906-8
Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N, Deng S, Liddelow SA, Zhang C, Daneman R, Maniatis T, Barres BA, Wu JQ.
J Neurosci. 2014 Sep 3;34(36):11929-47
Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis.
Yuen TJ, Silbereis JC, Griveau A, Chang SM, Daneman R, Fancy SP, Zahed H, Maltepe E, Rowitch DH.
Cell. 2014 Jul 17;158(2):383-96
Regulation of intrinsic axon growth ability at retinal ganglion cell growth cones.
Steketee MB, Oboudiyat C, Daneman R, Trakhtenberg E, Lamoureux P, Weinstein JE, Heidemann S, Barres BA, Goldberg JL.
Invest Ophthalmol Vis Sci. 2014 Jun 6;55(7):4369-77
Purification and culture of central nervous system pericytes.
Zhou L, Sohet F, Daneman R.
Cold Spring Harb Protoc. 2014 Jun 2;2014(6):581-3
Purification of pericytes from rodent optic nerve by immunopanning.
Zhou L, Sohet F, Daneman R.
Cold Spring Harb Protoc. 2014 Jun 2;2014(6):608-17
Purification of endothelial cells from rodent brain by immunopanning.
Zhou L, Sohet F, Daneman R.
Cold Spring Harb Protoc. 2014 Jan 1;2014(1):65-77
Purification and culture of central nervous system endothelial cells.
Zhou L, Sohet F, Daneman R.
Cold Spring Harb Protoc. 2014 Jan 1;2014(1):44-6
2013
Development, maintenance and disruption of the blood-brain barrier.
Obermeier B, Daneman R, Ransohoff RM.
Nat Med. 2013 Dec;19(12):1584-96
'Sealing off the CNS': cellular and molecular regulation of blood-brain barriergenesis.
Siegenthaler JA, Sohet F, Daneman R.
Curr Opin Neurobiol. 2013 Dec;23(6):1057-64
Foxc1 is required by pericytes during fetal brain angiogenesis.
Siegenthaler JA, Choe Y, Patterson KP, Hsieh I, Li D, Jaminet SC, Daneman R, Kume T, Huang EJ, Pleasure SJ.
Biol Open. 2013 May 20;2(7):647-59
Transporters of the blood-brain and blood-CSF interfaces in development and in the adult.
Saunders NR, Daneman R, Dziegielewska KM, Liddelow SA.
Mol Aspects Med. 2013 Apr-Jun;34(2-3):742-52
Genetic mouse models to study blood-brain barrier development and function.
Sohet F, Daneman R.
Fluids Barriers CNS. 2013 Jan 10;10(1):3
2012
The blood-brain barrier in health and disease.
Daneman R.
Ann Neurol. 2012 Nov;72(5):648-72
Fernández-López D, Faustino J, Daneman R, Zhou L, Lee SY, Derugin N, Wendland MF, Vexler ZS.
J Neurosci. 2012 Jul 11;32(28):9588-600
2011
Development of a method for the purification and culture of rodent astrocytes.
Foo LC, Allen NJ, Bushong EA, Ventura PB, Chung WS, Zhou L, Cahoy JD, Daneman R, Zong H, Ellisman MH, Barres BA.
Neuron. 2011 Sep 8;71(5):799-811
Crespo O, Kang SC, Daneman R, Lindstrom TM, Ho PP, Sobel RA, Steinman L, Robinson WH.
J Clin Immunol. 2011 Dec;31(6):1010-20
2010
Daneman R, Zhou L, Agalliu D, Cahoy JD, Kaushal A, Barres BA.
PLoS One. 2010 Oct 29;5(10):e13741
Pericytes are required for blood-brain barrier integrity during embryogenesis.
Daneman R, Zhou L, Kebede AA, Barres BA.
Nature. 2010 Nov 25;468(7323):562-6
2009
The gut immune barrier and the blood-brain barrier: are they so different?
Daneman R, Rescigno M.
Immunity. 2009 Nov 20;31(5):722-35
Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis.
Daneman R, Agalliu D, Zhou L, Kuhnert F, Kuo CJ, Barres BA.
Proc Natl Acad Sci U S A. 2009 Jan 13;106(2):641-6
2008
Dugas JC, Mandemakers W, Rogers M, Ibrahim A, Daneman R, Barres BA.
J Neurosci. 2008 Aug 13;28(33):8294-305
2005
The blood-brain barrier--lessons from moody flies.
Daneman R, Barres BA.
Cell. 2005 Oct 7;123(1):9-12